Recombinant Human Trefoil Factor1 貨號(hào):300-60 細(xì)胞因子
胞因子受體存在著可溶性形式，掌握可溶性細(xì)胞因子受體產(chǎn)生的規(guī)律及其生理和病理意義，必將擴(kuò)展人們對(duì)細(xì)胞因子網(wǎng)絡(luò)作用的認(rèn)識(shí)。檢測(cè)細(xì)胞因子及其受體的水平已成為基礎(chǔ)和臨床免疫學(xué)研究中的一個(gè)重要的方面。Catalog Number:
Catalog Number:
300-60
Synonyms:
pS2 protein, HP1.A, Breast Cancer Estrogen-Inducible protein （BCEI）, PNR2
Description:
The Trefoil Factor peptides （TFF1, TFF2 and TFF3） are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa and functions as a gastric-specific tumor suppressor gene. Recombinant human TFF1 is a 6.7 kDa monomeric protein consisting of a 60 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
AA Sequence:
EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human MCF-7 cells using a concentration 5-10 μg/ml.
Cross Reactivity:
Human
Research Interests:
 | Cancer |  | Stem Cells & Differentiation |
Country of Origin:
USA
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